AboutWhat does the meme depict?

Louis Looking At Pill Bottle is an exploitable image macro derived from the TV show Family Guy. In the template, Lois Griffin appears fraught and disheveled as she sits at a dining table, intently staring at a prescription pill bottle she holds. This scene is commonly used to represent humorous or exaggerated connections between a person and an object of considerable temptation by altering the label on the pill bottle to include various humorous and context-specific text.

OriginWho did it first?

The meme originates from an episode of Family Guy titled "Prescription Heroine," which was aired on March 27th, 2022, during the show's 20th season. The specific scene used for the meme features Lois grappling with an urge to consume prescription pain medication, as she looks intensely at a pill bottle. A YouTube clip of this scene was uploaded by user R M on April 4th, 2022. Following this, the meme gained more popularity when user @BacockObama posted an edited screencap from the episode on Twitter (now X) on August 7th, 2022, humorously labeling the pill bottle as 'zendaya every episode of euphoria.'^[1]

Origin: 2022